·
Preservation of both morphology and
biomolecules
·
Fixation and paraffin embedding without
formalin
·
Improved molecular results from fixed
tissues
·
Tissue can be stored and archived for later
processing
·
RNA, miRNA, DNA, and/or proteins from one
sample
PAXgene Tissue Containers are
dual-cavity containers prefilled with 2 reagents. PAXgene Tissue FIX
rapidly penetrates and fixes the tissue, preserving tissue morphology.
Fixation is comparable to formalin fixation, but without
the destructive nucleic acid and protein crosslinking and degradation.
After fixation, the tissue is transferred to
PAXgene Tissue STABILIZER in the same container.
Nucleic acids, proteins, and morphology of the
sample are stable up to 7 days at room temperature and for longer
periods at 2-8°C, or even at -20°C and -80°C. Stabilized samples
can be embedded in paraffin for histological studies. PAXgene Tissue
Kits and supplementary protocols provide efficient subsequent
purification of RNA, miRNA, DNA, and/or proteins from the same
sample.
